AssayIndex

SWB-2503-P7565

Retatrutide · 15 mg declared · Shanghai Wibson Biotechnology Co., Ltd. · manufactured 22 Mar 2025

CHARACTERISED
Lot code
SWB-2503-P7565
Supplier
SWB — Shanghai Wibson Biotechnology Co., Ltd.
Compound
Retatrutide
Compound class
Incretin analogues and co-agonists
Declared label claim
15mg
Manufacture date
22 Mar 2025
Index quarter
2025-Q2
Independent assays
11
Laboratories involved
Janoshik, Kestrel, PeptideMeter, Medutest
Provenance mix
Buyer-sourced ×10 · Supplier-supplied ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 11
Median purity 98.54% n=11
Spread (max − min) 1.46pp n=11
Standard deviation 0.403pp n=11
95.596.397.197.998.799.5100.3This lot (SWB-2503-P7565)This lot (SWB-2503-P7565): Q1 98.25, median 98.54, Q3 98.75, n=11n=11All RetatrutideAll Retatrutide: Q1 97.96, median 98.37, Q3 98.82, n=492outlier 95.81outlier 96.13outlier 96.29outlier 96.32outlier 96.46outlier 96.48outlier 96.52outlier 96.54outlier 96.54outlier 96.63outlier 96.64n=492 Purity (% area)
Figure 1. This lot's independent purity results against the whole Retatrutide record set in the index. The vertical line is the index acceptance specification for the incretin analogues and co-agonists class, 96.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 11

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-020050SWB-2503-P7565Janoshik2025-Q298.174.9799.9Buyer-sourced1MARGINAL
AX-2025-020051SWB-2503-P7565Kestrel2025-Q299.414.90Supplier-supplied2MARGINAL
AX-2025-020052SWB-2503-P7565PeptideMeter2025-Q298.765.0493.9Buyer-sourced1MARGINAL
AX-2025-020053SWB-2503-P7565Kestrel2025-Q298.654.9989.6Buyer-sourced2MARGINAL
AX-2025-020054SWB-2503-P7565PeptideMeter2025-Q298.154.69Buyer-sourced1MARGINAL
AX-2025-020055SWB-2503-P7565Medutest2025-Q298.324.91Buyer-sourced1MARGINAL
AX-2025-020056SWB-2503-P7565PeptideMeter2025-Q298.534.94Buyer-sourced1MARGINAL
AX-2025-020057SWB-2503-P7565Kestrel2025-Q298.824.99Buyer-sourced2FAIL
AX-2025-020058SWB-2503-P7565Medutest2025-Q298.755.08Buyer-sourced1MARGINAL
AX-2025-020059SWB-2503-P7565PeptideMeter2025-Q297.955.1894.3Buyer-sourced1MARGINAL
AX-2025-020060SWB-2503-P7565Janoshik2025-Q298.544.52Buyer-sourced1MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik298.17, 98.5498.3630min+0.0098.36
Kestrel399.41, 98.65, 98.8298.8215min+0.2498.58
PeptideMeter498.76, 98.15, 98.53, 97.9598.3428min-0.0598.39
Medutest298.32, 98.7598.5325min+0.0898.45

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.098.17divergence +0.46 pp vs batch median
Total impurities (% area)1.001.83
Largest single impurity (% area)not stated0.89
Water (%)2.64.97
Counter-ion (%)not stated10.01
Peptide content (%w/w)92.684.05
Endotoxin (EU/mg)not statednot determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
[D-Aib2]-diastereomer11 / 110.610.12–0.91
des-Aib20 analogue11 / 110.340.03–0.51
C18 diacid regioisomer11 / 110.150.04–0.20
retatrutide dimer10 / 110.040.03–0.06
incomplete Fmoc removal (+222 Da)6 / 110.100.08–0.12
truncated (5-39)6 / 110.040.03–0.05
aspartimide (−18 Da)5 / 110.790.40–1.19
oxidised Trp (+16 Da)3 / 110.050.04–0.06
Section 7

What this rollup does not establish