AssayIndex
Cross-section

Desmopressin by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Desmopressin, with a class minimum gradient of 15 min, the method is a live explanation.

22 recordsmedian 98.83 %spec 98.5 %
LaboratoryReportsGradientMS resolutionMedian purity %Published bias (pp)Bias-adjustedMethod suitability
Janoshik1430minHigh98.78+0.0098.78ADEQUATE
Medutest4 n=425minUnit98.75+0.0898.67ADEQUATE
PeptideMeter2 n=228minHigh99.48, 99.57-0.05—ADEQUATE
VendorInvestigate1 n=132minHigh98.15-0.11—ADEQUATE
Nordanalyt1 n=135minHigh99.35+0.02—ADEQUATE
Kestrel015minUnit—+0.24—ADEQUATE
98.198.598.899.199.499.7100.1JanoshikJanoshik: Q1 98.57, median 98.78, Q3 99.52, n=14n=14PeptideMeterPeptideMeter: Q1 99.50, median 99.53, Q3 99.55, n=2n=2MedutestMedutest: Q1 98.68, median 98.75, Q3 99.11, n=4outlier 99.93n=4 Purity (% area)
Figure. Desmopressin purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.