AssayIndex
Cross-section

MGF by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for MGF, with a class minimum gradient of 15 min, the method is a live explanation.

37 recordsmedian 99.29 %spec 97.5 %
LaboratoryReportsGradientMS resolutionMedian purity %Published bias (pp)Bias-adjustedMethod suitability
Janoshik1830minHigh99.34+0.0099.34ADEQUATE
PeptideMeter828minHigh99.22-0.0599.27ADEQUATE
Medutest4 n=425minUnit98.87+0.0898.79ADEQUATE
Nordanalyt3 n=335minHigh99.29+0.0299.27ADEQUATE
VendorInvestigate2 n=232minHigh99.39, 98.57-0.11—ADEQUATE
Kestrel2 n=215minUnit98.56, 99.19+0.24—ADEQUATE
97.998.298.699.099.399.7100.1JanoshikJanoshik: Q1 99.05, median 99.34, Q3 99.68, n=18n=18PeptideMeterPeptideMeter: Q1 98.93, median 99.22, Q3 99.50, n=8outlier 98.02n=8MedutestMedutest: Q1 98.53, median 98.87, Q3 99.14, n=4n=4VendorInvestigateVendorInvestigate: Q1 98.77, median 98.98, Q3 99.19, n=2n=2NordanalytNordanalyt: Q1 98.84, median 99.29, Q3 99.52, n=3n=3KestrelKestrel: Q1 98.72, median 98.88, Q3 99.03, n=2n=2 Purity (% area)
Figure. MGF purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.