AssayIndex
Cross-section

Pramlintide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Pramlintide, with a class minimum gradient of 25 min, the method is a live explanation.

15 recordsmedian 99.10 %spec 97.5 %
LaboratoryReportsGradientMS resolutionMedian purity %Published bias (pp)Bias-adjustedMethod suitability
PeptideMeter6 n=628minHigh99.10-0.0599.15ADEQUATE
Janoshik4 n=430minHigh99.16+0.0099.16ADEQUATE
VendorInvestigate3 n=332minHigh99.10-0.1199.21ADEQUATE
Nordanalyt1 n=135minHigh98.52+0.02—ADEQUATE
Kestrel1 n=115minUnit99.52+0.24—BELOW CLASS MINIMUM
Medutest025minUnit—+0.08—ADEQUATE
98.798.899.099.299.499.699.8JanoshikJanoshik: Q1 98.90, median 99.16, Q3 99.39, n=4n=4PeptideMeterPeptideMeter: Q1 98.91, median 99.10, Q3 99.34, n=6n=6VendorInvestigateVendorInvestigate: Q1 98.93, median 99.10, Q3 99.14, n=3n=3 Purity (% area)
Figure. Pramlintide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.