Sermorelin impurity profile
Every named species the index has reported alongside Sermorelin, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
Median total impurities
0.95%
n=58
Median largest single
0.49%
n=58
Worst single observed
1.13%
n=58
Named species observed
4 / 4
n=4
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| truncated (1-25) | -1.04 | -455.248 | 100% | 0.13 | 0.83 |
| deamidated Asn8 (+1 Da) | -0.30 | +0.984 | 98% | 0.24 | 1.13 |
| aspartimide (−18 Da) | +0.36 | -18.011 | 98% | 0.11 | 0.72 |
| des-Tyr1 (−163 Da) | -0.52 | -163.063 | 97% | 0.18 | 0.88 |
truncated (1-25)
- Retention offset from the main peak
- -1.04 min on RG-2
- Mass difference
- -455.248 Da
- Reported in
- 58 of 58 records (100 %)
- Level when reported
- median 0.13 %, max 0.83 %
- How it separates
- Baseline-resolved on the reference method.
deamidated Asn8 (+1 Da)
- Retention offset from the main peak
- -0.30 min on RG-2
- Mass difference
- +0.984 Da
- Reported in
- 57 of 58 records (98 %)
- Level when reported
- median 0.24 %, max 1.13 %
- How it separates
- Baseline-resolved on the reference method.
aspartimide (−18 Da)
- Retention offset from the main peak
- +0.36 min on RG-2
- Mass difference
- -18.011 Da
- Reported in
- 57 of 58 records (98 %)
- Level when reported
- median 0.11 %, max 0.72 %
- How it separates
- Baseline-resolved on the reference method.
des-Tyr1 (−163 Da)
- Retention offset from the main peak
- -0.52 min on RG-2
- Mass difference
- -163.063 Da
- Reported in
- 56 of 58 records (97 %)
- Level when reported
- median 0.18 %, max 0.88 %
- How it separates
- Baseline-resolved on the reference method.
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- Asn8 deamidation — half-life of days in neutral aqueous solution at room temperature
- Asp3 aspartimide