Cross-section

Tesamorelin by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Tesamorelin, with a class minimum gradient of 15 min, the method is a live explanation.

18 recordsmedian 98.29 %spec 97.0 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
PeptideMeter	6 n=6	28min	High	98.19	-0.05	98.24	ADEQUATE
Janoshik	5 n=5	30min	High	98.43	+0.00	98.43	ADEQUATE
Medutest	4 n=4	25min	Unit	98.30	+0.08	98.22	ADEQUATE
Kestrel	2 n=2	15min	Unit	98.91, 98.34	+0.24	—	ADEQUATE
VendorInvestigate	1 n=1	32min	High	98.13	-0.11	—	ADEQUATE
Nordanalyt	0	35min	High	—	+0.02	—	ADEQUATE

Figure. Tesamorelin purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.