AssayIndex
Chromatography

Resolution (R)

Separation between two peaks: R = 2(t₂ − t₁)/(w₁ + w₂). R = 1.5 is baseline resolution. The index computes and reports R to the nearest named impurity on every record that has one, and applies no acceptance criterion to it — resolution to whichever impurity happens to elute closest is a property of the compound and the gradient, not a system-suitability requirement.

Related terms

Asymmetry factor (As)
Peak shape measure taken at 10 % of peak height: the width of the rear half divided by the width of the front half. Symmetric = 1.00. Above 1.50 the index marks integration unreliable.
see also Rule AX-R12
Valley
The minimum of the detector signal between two adjacent peaks. Valley height relative to the smaller peak determines whether the two can be reliably integrated separately.

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.