Cross-section

AOD-9604 by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for AOD-9604, with a class minimum gradient of 15 min, the method is a live explanation.

96 recordsmedian 99.29 %spec 98.0 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	45	30min	High	99.37	+0.00	99.37	ADEQUATE
PeptideMeter	21	28min	High	99.00	-0.05	99.05	ADEQUATE
VendorInvestigate	12	32min	High	99.02	-0.11	99.13	ADEQUATE
Medutest	7 n=7	25min	Unit	99.35	+0.08	99.27	ADEQUATE
Nordanalyt	6 n=6	35min	High	99.09	+0.02	99.07	ADEQUATE
Kestrel	5 n=5	15min	Unit	99.42	+0.24	99.18	ADEQUATE

Figure. AOD-9604 purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.