AssayIndex
Cross-section

AOD-9604 impurity profile

Every named species the index has reported alongside AOD-9604, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.

96 recordsmedian 99.29 %spec 98.0 %
Median total impurities 0.71% n=96
Median largest single 0.39% n=96
Worst single observed 1.15% n=96
Named species observed 4 / 4 n=4
Named speciesΔRT (min)Δ mass (Da)Seen inMedian % areaMax % area
open-chain (reduced disulfide, +2 Da)-0.61+2.01698%0.151.05
Met sulfoxide (+16 Da)-0.44+15.99598%0.130.55
des-Tyr AOD (−163 Da)-0.84-163.06397%0.141.05
AOD dimer+2.10+1813.85295%0.141.15

open-chain (reduced disulfide, +2 Da)

Retention offset from the main peak
-0.61 min on RG-2
Mass difference
+2.016 Da
Reported in
94 of 96 records (98 %)
Level when reported
median 0.15 %, max 1.05 %
How it separates
Baseline-resolved on the reference method.

Met sulfoxide (+16 Da)

Retention offset from the main peak
-0.44 min on RG-2
Mass difference
+15.995 Da
Reported in
94 of 96 records (98 %)
Level when reported
median 0.13 %, max 0.55 %
How it separates
Baseline-resolved on the reference method.

des-Tyr AOD (−163 Da)

Retention offset from the main peak
-0.84 min on RG-2
Mass difference
-163.063 Da
Reported in
93 of 96 records (97 %)
Level when reported
median 0.14 %, max 1.05 %
How it separates
Baseline-resolved on the reference method.

AOD dimer

Retention offset from the main peak
+2.10 min on RG-2
Mass difference
+1813.852 Da
Reported in
91 of 96 records (95 %)
Level when reported
median 0.14 %, max 1.15 %
How it separates
Baseline-resolved on the reference method.

Degradation pathways

Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.

  • disulfide reduction
  • Met oxidation