GHRP-2 impurity profile
Every named species the index has reported alongside GHRP-2, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
Median total impurities
0.71%
n=110
Median largest single
0.36%
n=110
Worst single observed
1.16%
n=110
Named species observed
4 / 4
n=4
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| oxidised Trp (+16 Da) | -0.36 | +15.995 | 94% | 0.19 | 0.95 |
| [D-2-Nal]-epimer | -0.14 | mass-identical | 89% | 0.12 | 0.51 |
| C-terminal free acid (+1 Da) | +0.16 | +0.984 | 88% | 0.07 | 1.16 |
| des-Lys (−128 Da) | -0.24 | -128.095 | 87% | 0.15 | 0.87 |
oxidised Trp (+16 Da)
- Retention offset from the main peak
- -0.36 min on RG-2
- Mass difference
- +15.995 Da
- Reported in
- 103 of 110 records (94 %)
- Level when reported
- median 0.19 %, max 0.95 %
- How it separates
- Baseline-resolved on the reference method.
[D-2-Nal]-epimer
- Retention offset from the main peak
- -0.14 min on RG-2
- Mass difference
- mass-identical — chromatography only
- Reported in
- 98 of 110 records (89 %)
- Level when reported
- median 0.12 %, max 0.51 %
- How it separates
- Chromatography only. A gradient long enough to separate it; no mass spectrometer of any resolution will.
C-terminal free acid (+1 Da)
- Retention offset from the main peak
- +0.16 min on RG-2
- Mass difference
- +0.984 Da
- Reported in
- 97 of 110 records (88 %)
- Level when reported
- median 0.07 %, max 1.16 %
- How it separates
- Close-eluting on the reference method, and merged with the main peak on a short gradient. The index prints the resolution figure for such a pair and applies no criterion to it — where the two are not separated, what matters is that the integration convention is stated.
des-Lys (−128 Da)
- Retention offset from the main peak
- -0.24 min on RG-2
- Mass difference
- -128.095 Da
- Reported in
- 96 of 110 records (87 %)
- Level when reported
- median 0.15 %, max 0.87 %
- How it separates
- Close-eluting on the reference method, and merged with the main peak on a short gradient. The index prints the resolution figure for such a pair and applies no criterion to it — where the two are not separated, what matters is that the integration convention is stated.
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- Trp oxidation
- C-terminal amide hydrolysis