Cross-section

MK-677 (Ibutamoren mesylate) by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for MK-677 (Ibutamoren mesylate), with a class minimum gradient of 15 min, the method is a live explanation.

143 recordsmedian 99.49 %spec 98.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	60	30min	High	99.50	+0.00	99.50	ADEQUATE
PeptideMeter	33	28min	High	99.45	-0.05	99.50	ADEQUATE
Medutest	20	25min	Unit	99.61	+0.08	99.53	ADEQUATE
Kestrel	12	15min	Unit	99.73	+0.24	99.50	ADEQUATE
Nordanalyt	10	35min	High	99.41	+0.02	99.39	ADEQUATE
VendorInvestigate	8	32min	High	99.43	-0.11	99.54	ADEQUATE

Figure. MK-677 (Ibutamoren mesylate) purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.